INCREASED OXPHOS ACTIVITY PRECEDES RISE IN GLYCOLYTIC RATE IN H-RASV12/E1A TRANSFORMED FIBROBLASTS THAT DEVELOP A WARBURG PHENOTYPE

Increased OXPHOS activity precedes rise in glycolytic rate in H-RasV12/E1A transformed fibroblasts that develop a Warburg phenotype

Abstract Background The Warburg phenotype in cancer cells has been long recognized, but there is still limited insight in the consecutive metabolic alterations that characterize its establishment.We obtained better understanding of the coupling between metabolism and malignant transformation by studying mouse embryonic fibroblast-derived cells with

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Over-the-counter mouthwash use, nitric oxide and hypertension risk

Purpose: Mouthwash is used by a large population.Short-term clinical trials have shown that antibacterial mouthwash deplete oral nitrate-reducing bacteria, and decrease systemic nitric oxide bioavailability.Our previous publication from the San Juan Overweight Adults Longitudinal Study (SOALS) was the first to show frequent over-the-counter mouthwa

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A Cooperative City. A dream Come True

The article explores the process of creating a large cooperative housing complex in a district of New York.It highlights the unique circumstances Bird Feeders that made the cooperative City project possible in the United States.The article also examines the efforts of European countries to foster urban residents’ involvement in urban development.

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Effects of selection for cooperation and attention in dogs

Abstract Background It has been suggested that the functional similarities in the socio-cognitive behaviour of dogs and humans emerged as a consequence of comparable environmental selection pressures.Here we use a novel approach to account Laptop for the facilitating effect of domestication in dogs and reveal that selection for two factors under ge

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